"The Real Problem is Reproducibility": Doc-to-Doc with Retraction Watch Co-Founder Ivan Oransky

"The Real Problem is Reproducibility": Doc-to-Doc with Retraction Watch Co-Founder Ivan Oransky

Retractions in the scientific literature occur for a variety of reasons, ranging from benign error to truly malignant fraud. Whatever the cause, retractions are tracked by Retraction Watch, a blog that seeks to provide insight into the scientific method by investigating some of its most visible failures.

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"What Used to be Fraud is Now Alternative Medicine": Doc-to-Doc with Steve Novella, MD

"What Used to be Fraud is Now Alternative Medicine": Doc-to-Doc with Steve Novella, MD

Dr. Steven Novella is a faculty member in the Yale School of Medicine and host of the wildly popular podcast "Skeptic's Guide to the Universe". I got to sit down with him to talk about science-based medicine, snake oil, and dealing with patients' occasionally strange beliefs.

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Does Health Insurance Save Lives?

Does Health Insurance Save Lives?

If health insurance reduces all-cause mortality, in a causal way, then policies which increase the number of uninsured may actually cost lives. In this deep dive, we examine the data surrounding that putative causal pathway. For the video version, click here.

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Paying Patients for HIV Control

Paying Patients for HIV Control

A study appearing in JAMA Internal Medicine found that paying patients with HIV to keep their viral load under control modestly, but significantly, improved that control. But physicians often have issues with financial incentive programs... 

For the video version, click here.

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Fraud in Medical Research: Understanding the Carlisle Approach

Fraud in Medical Research: Understanding the Carlisle Approach

A "bombshell" paper appearing in the journal Anesthaesia uses a simple statistical test to suggest that a significant proportion of medical studies - some from our most prestigious journals - may be fabrications. But the story is not a clear cut as it seems. For the video version, click here.

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The Link Between Persistent Pain and the Development of Dementia

The Link Between Persistent Pain and the Development of Dementia

A study appearing in JAMA Internal Medicine links persistent pain with progressive cognitive decline and dementia. But the mechanism is quite unclear. There are actually a few possibilities. For the video version, click here.

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Dads Want Their Daughters to be Happy. Their Sons? Not So Much.

Dads Want Their Daughters to be Happy. Their Sons? Not So Much.

A study appearing in the journal Behavioral Neuroscience found significant differences in the ways that dad treat their daughters compared to their sons. And some of that difference can be seen on MRI.

For the video version, click here.

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Propensity Scores: Observational Data and Wishful Thinking

Propensity Scores: Observational Data and Wishful Thinking

Propensity score methods attempt to make observational data look like a randomized trial. But there are some big limitations that need to be considered before we jump on the bandwagon. For the video version, click here.

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Steroids Lose to Saline in Knee Osteoarthritis Trial

Steroids Lose to Saline in Knee Osteoarthritis Trial

A randomized trial appearing in the Journal of the American Medical Association calls into question the common - and lucrative - practice of steroid injection for osteoarthritis of the knee. All you need to know, in 150 Seconds. For the video version, click here.

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